Author: Ahmed Ibrahim Rashid, Nedhal Suhail Zbar, Moyassar Basil Hadi Al-Shaibani
Page: 1-13
Published online: 04 Jan 2023
Abstract:
Previous studies have extensively investigated the role of glutaminase as a source for energy for cancer cells. It is well documented that glutaminase convert glutamine to glutamate which is used as a source for energy alongside with glucose and fatty acids. Therefore, previous studies have hypothesized that inhibition of glutaminase will block energy sources and reduce proliferation of cancer cells. To best of our knowledge, none of these studies have investigated the exact level of glutaminase...