Journal

ACE Journal of Research Studies in Biosciences

  • ISSN Print: 2520-3916, ISSN Online:
  • Start Year: 2021
  • Volume: 5 (2025), Issue: 1

Evaluating the Effectiveness of Co2 Laser, Versus Radiofrequency Therapy for Genitourinary Syndrome of Menopause

Author: Huda Mahmoud Alfatal
Page: 1-8
Published online: 26 Aug 2025

https://doi.org/10.36478/acejrsb.2025.1.8

Abstract:

Post menopause, estrogen deficiency results in vulvovaginal atrophy. Scientists and gynecologists regard the fractional CO2 laser as a disruptive technology because of its novelty and innovative potential to transform healthcare, and it may enhance feminine health. Radiofrequency employs electrical energy in the form of heat to ablate tissue, like fractional laser technology, resulting in minimal tissue damage and expedited recovery. monopolar radiofrequency previously modulated injury‐induced inflammation and re‐epithelialization. Evaluating the Efficacy of Fractional CO2 Laser Compared to Radiofrequency in the Management of Vulvovaginal Atrophy. This comparative study was conducted from June to October 2024 at the University of Baghdad Institute of Laser for Postgraduate Studies. Radiofrequency and fractional CO2 laser treatments were given to 20 women. Sexually active postmenopausal women aged 48–55 with two or more genito‐urinary symptoms of menopause (GSM), vulvovaginal atrophy and over one year of amenorrhea were eligible. Genital neoplasms, active infections, previous genital cancer treatment, and stage II or higher organ prolapse were excluded. Before treatment, the Visual Analogue Scale was used to assess pain, and the Vaginal Health Index to assess vaginal symptoms. The Female Sexual Function Index(FSFI) was also assessed. Patients received four CO2 laser sessions at four‐week intervals and radiofrequency treatments received four session lasted 25 minutes every 14–16 days.(2 weeks in average). The t‐test showed no significant difference in VAS (visual analogue scores ) between groups before treatment. Both groups' VAS scores decreased post‐treatment, with no significant difference, as shown by the t‐test's p‐value greater than 0.05. The two groups VHI(Vahinal health index) ,did not differ statistically before treatment. The VHI showed a statistically significant difference between the two groups, with the CO2 laser group scoring higher (t‐test p‐value 0.017). FSFI scores, pre‐ and post‐treatment did not differ between groups, as the t‐test showed a p‐value greater than 0.05. Both cohorts' FSFI scores improved after treatment. It can be concluded that both laser therapy and radiofrequency (RF) treatments are effective in alleviating symptoms of vaginal atrophy (VVA).