Author:
Shaymaa A. Kjayoon, Dawood S. Mahdi and Ihsan E. Alsaimary
Page: 53-56
Published online: 10 Jul 2024
https://doi.org/acejphcm.2024.53.56
Toxoplasmosis is one of the main causes of miscarriage in pregnant women. The aim of this study is to investigate the chemokines concentration of CCL2, CCL4 and CXCL5 and the correlation with aborted women infected with toxoplasmosis and the relation of these chemokines with each other and with disease among an abortion. The total number of 166 serum samples (75 seropositive, 45 seronegative and 46 control), aged between 17‐42 years who visited Basra Hospital for women and Children in Basra Province during the period between November 2022 to May 2023. This research is a case‐control study on 160 serum samples from seropositive and negative aborted women and healthy control (women who have a normal delivery with, no history of abortion). The level of CCL2, CCL4 and CXCL5 were estimated in seropositive aborted cases compared with another groups by using ELISA method. The results show the mean concentration of CCL2 (79.8 pg/ml) was less than other groups, while CCL4 have concentration (173.1pg/ml) high in positive aborted women with significant than other groups. Further, the concentration of CXCL5 of seropositive aborted women was less than other groups with low statistically differ. Our study appear there were no statistically significant differences between all categories.