ACE Research Journal of Microbiology and Biotechnology

  • ISSN Print: 2520-3975, ISSN Online:
  • Start Year: 2021
  • Volume: 3 (2023), Issue: 2

The Role of Lactate dehydrogenase c (LDHc) on Semen Parameters and Testosterone Concentration in male infertility at Al-Najaf Province

Author: Sajjad Saleh Hameed and Mohammed Abdulrazzaq Assi
Page: 34-38
Published online: 31 Jan 2024


Background: The lactate dehydrogenase C (LDHc) isoenzyme is a key enzyme in spermatogenesis and sperm parameter metabolism. Testosterone is one of the most important factors in germ cell growth. Changes in serum gonadotropins are frequently linked to abnormal spermatogenesis. Objectives: The goal of this study is to correlate LDHc and serum testosterone levels with sperm parameters. and (regard by enzyme-linked immunosorbent assay (ELISA) kit in fertile and infertile men in Najaf City, Iraq. Material and Methods: A total of 90 participants (45 infertile and 45 fertile men) were mean age (40.02) years in control fertility male, whilst were mean age as infertile (40.22) years included in the current study. The patients were sub-grouped into: 45 infertile with semen abnormal oligozoospermia , azoospermia. , asthenozoospermia and teratozoospermia patients, it used for measuring the concentration and parameters ECM1and serum testosterone by Elisa kit.. Results: The statistical analysis revealed that the differences between the two groups were very significant (P-value0.05). The level of LDHc in the infertile group was lower in concentration than the control group with statistically significant differences (P-value