TY  - JOUR
T1  - Formulation and Development of <i>Garcina Indica</i> Nanosuspension for Weight Loss
AU - Kinani, Ahmad AB
        AU - Al‐Bayati, Mohammed H.
        
JO  - ACE Journal of Research Studies in Biosciences
VL  - 5
IS  - 1
SP  - 23
EP  - 29
PY  - 2025
DA  - 2001/08/19
SN  - 2520-3916
DO  - 10.36478/acejrsb.2025.23.29
UR  - https://theacepublications.com/article-detail.php?art=269-ACE-JRSB
KW  - Garcinia indica
KW  - nanosuspension
KW  - hydroxycitric acid (HCA)
KW  - tween 80
KW  - poloxamer 407
KW  - zeta potential
KW  - SEM
AB  - This study aimed to improve the stability and solubility of <i>Garcinia
indica's</i> bioactive compounds, the HCA part is forming the aqueous
extract into a nanosuspension using Poloxamer 407 and Tween 80 (HPH)
through high‐pressure homogenization. The optimized nanosuspension
formula is estimated by SEM (to study the morphology and size; the
spherical nanoparticles should be between 400‐200 nm) and Zeta
Potential (‐35 mV to indicate the stability), to demonstrate the
aggregation prevention and the effective particle size reduction. HPLC
study is confirmed HCA loading of active drug. This study shows promise
for enhancing the physicochemical properties of <i>Garcinia indica's</i>
bioactive compounds for pharmaceutical applications, and the study can
be supported by further investigation <i>in‐vitro</i> and <i>in‐vivo</i> studies.
ER  -